2024 Grpe protein homolog mitochondrial

Grpe protein homolog mitochondrial

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August undefined, 2024

WebGrpe protein homolog, mitochondrial; GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner : 0.952: Hsp90: WebMar 30, 2024 · Mitochondrial GrpE (Mge1p) is a mitochondrial cochaperone essential for viability of the yeast Saccharo-myces cerevisiae.To study the role of Mge1p in the biogenesis of mitochondrial proteins, we isolated a conditional mutant allele of MGE1 which conferred a temperature-sensitive growth phenotype and led to the accumulation …

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WebPharos : Target Details - GRPEL1 Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein … fischer borna

Q0UL32 - UniProt

WebApr 11, 2024 · In multiple cancers, slow-dividing cancer cells generate ATP via mitochondrial oxidative phosphorylation . Besides, cancer stem cells, which are resistant to regular chemo- and radiotherapy, ... Aaron Ciechanover used yeast mutants to clone human homolog genes involved in protein ubiquitination, previously studied in the budding … WebMar 30, 2024 · We characterized a 24-kDa protein associated with matrix hsp70 (mt-hsp70) of Neurospora crassa and Saccharomyces cerevisiae mitochondria. By using specific antibodies, the protein was identified as MGE, a mitochondrial homolog of the prokaryotic heat shock protein GrpE. MGE extracted from mitochondria was quantitatively bound to … WebSummary Gene: Grpel1 (GrpE-like 1, mitochondrial) Rattus norvegicus Add Watcher Analyze General Array IDs Annotation Click to see Annotation Detail View Disease … fischer bottle gas

Mitochondrial Import of Dengue Virus NS3 Protease and Cleavage of

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WebApr 1, 2024 · GrpE protein homolog (GrpEL) is a nucleotide exchange factor that controls mtHSP70 in nonnative proteins folding in mitochondria (Konovalova et al., 2024; … WebEnter the email address you signed up with and we'll email you a reset link. camping proche bassin d\u0027arcachonWebApr 13, 2024 · The mitochondrial unfolded protein response (UPRmt) and mitophagy are two mitochondrial quality control (MQC) systems that work at the molecular and organelle levels, respectively, to maintain mitochondrial homeostasis. Under stress conditions, these two processes are simultaneously activated and compensate for each other when one … fischer bp shield anchor m10/59

"GrpE (Gro-P like protein E) is a bacterial nucleotide exchange factor that is important for regulation of protein folding machinery, as well as the heat shock response. It is a heat-inducible protein and during stress it prevents unfolded proteins from accumulating in the cytoplasm. Accumulation of unfolded proteins in the cytoplasm can lead to cell death. " - Grpe protein homolog mitochondrial

Grpe protein homolog mitochondrial

WebAug 17, 2024 · We also show that matrix-localized GrpE protein homolog 1 (GrpEL1), a cochaperone of mitochondrial Hsp70 (mtHsp70), is also the substrate of dengue virus protease, as observed in vitroand ex vivoin virus-infected cells and dengue virus-infected … WebNational Center for Biotechnology Information

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WebGrpE protein homolog 2, mitochondrial (GRPEL2) [NX_Q8TAA5] Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial … WebMar 9, 2024 · GrpE; HMGE; mt-GrpE#1 Summary Enables identical protein binding activity and unfolded protein binding activity. Predicted to be involved in protein import into mitochondrial matrix. Located in mitochondrial matrix and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2024] Expression

WebApr 10, 2024 · Intracytoplasmic-membrane development in alphaproteobacteria involves the homolog of the mitochondrial crista-developing protein Mic60 Curr Biol . 2024 Apr 10;33(7):1396. doi: 10.1016/j.cub.2024.03.049. WebGrpE protein homolog 1, mitochondrial Alternative names Mt-GrpE#1 Gene names Name Grpel1 Synonyms Grepel1 Organism names Organism Rattus norvegicus (Rat) Taxonomic identifier 10116 NCBI Taxonomic lineage

WebNX_Q9HAV7 - GRPEL1 - GrpE protein homolog 1, mitochondrial - Function. Essential component of the PAM complex, a complex required for the translocation of transit … WebGolgi integral membrane protein 4 (GIMPc) (Golgi phosphoprotein of 130 kDa) 1.777: 0.126: 0.000: O00746: Nucleoside diphosphate kinase, mitochondrial (NDK) (NDP kinase, mitochondrial) (NDPKD) 0.000: ... Mitochondrial import inner membrane translocase subunit TIM44: 0.092: 0.008: 0.000: O43809:

WebJun 1, 2002 · GrpE protein homolog 2, mitochondrial Gene GRPEL2 Status UniProtKB reviewed (Swiss-Prot) Organism Homo sapiens (Human) Amino acids 225 Protein …

WebThe eukaryotic cytosol does not contain GrpE per se because GrpE-like function is provided by the BAG1 protein, which acts as a nucleotide exchange factor for cytosolic Hsp70s. GrpE, which plays a prominent role in mitochondria, chloroplasts, and bacterial cytoplasms, is a fascinating molecule with an unusual quaternary structure. camping prices in yellowstoneWebgrpE protein homolog 1, mitochondrial; GrpE#1; GrpE1; mt-GrpE#1; stress-inducible chaperone mt-GrpE#1: RGD Orthologs: Human. Mouse. Chinchilla. Bonobo. Dog. Squirrel. Pig. Green Monkey. Naked Mole-Rat. Alliance Genes: More Info: more info ... More Info: Species Gene symbol and name Data Source Assertion derived from camping prinsenmeer astenWebMar 8, 2024 · In eukaryotes, only the mitochondrial Hsp70, not the cytosolic form, is GrpE dependent. Over-expression of Hsp70 molecular chaperones is important in suppressing toxicity of aberrantly folded proteins that occur in Alzheimer's disease (AD), Parkinson's disease (PD), amyotrophic lateral sclerosis, as well as several polyQ-diseases such as ... camping prien chiemsee hofbauerWebAbstract. The cochaperone GrpE functions as a nucleotide exchange factor to promote dissociation of adenosine 5'-diphosphate (ADP) from the nucleotide-binding cleft of … camping proche berck sur merWebAug 5, 2024 · GRPEL2 Knockdown Exerts Redox Regulation in Glioblastoma. The dimerization of GRPEL2 may activate the folding machinery responsible for protein … camping prices ontarioWebMar 9, 2024 · GrpE; HMGE; mt-GrpE#1 Summary Enables identical protein binding activity and unfolded protein binding activity. Predicted to be involved in protein import into … camping proche château de chambordWebProtein target information for GrpE protein homolog 1, mitochondrial (house mouse). Find diseases associated with this biological target and compounds tested against it in … fischer bowling club